Thanks so much for this question! This is obviously something that should be taken to the Lord in prayer and ask for discernment from the Holy Spirit. You can find scriptures that “justify” either position. We can look at the example of Joseph storing up in preparation for times of famine (Gen 41:34-36). If the desire is to allow these funds to have an impact for years to come or weather upcoming financial headwinds these ministries may face, then maintaining the principal and only using the interest may be a wise option. Alternatively, we see in 1 John 3:17 “if anyone has the world’s goods and sees his brother in need, yet closes his heart against him, how does God’s love abide in him?” Would spending down the balance allow you to better address the needs around you? Are the ministries serving those needs prepared to receive the influx of resources? More money is not always the answer and can actually harm a ministry/non-profit in the long run if not careful. Also, consider that these options may not be mutually exclusive. If there are immediate needs that can be addressed effectively using some of the balance you can still preserve the remaining principal to earn interest.

Chad has provided excellent biblical references. We work with several non-profits (providing guidance as financial advisors) and we typically recommend a “total return” approach to investing. https://investor.vanguard.com/investor-resources-education/news/total-return-investing-a-superior-approach-for-income-investors Most importantly, you must match the ministries goals and timeline for the funds, with how the money is invested. Failing to properly align these components usually leads to poor performance and having to sell to spend the money at the wrong time. If you have more questions you can reach out to me.